Phenotypic and Genotypic Analysis of In Vitro Selected Artemisinin-Resistant
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چکیده
Progeny of Plasmodium falciparum 2 Matthew S. Tucker**, Tina Mutka, Kansas Sparks, Janus Patel, and Dennis E. Kyle* 3 Department of Global Health, College of Public Health, University of South Florida, 3720 4 Spectrum Blvd, Tampa, FL. 33612, USA 5
منابع مشابه
Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum.
Emergence of artemisinin resistance in Cambodia highlights the importance of characterizing resistance to this class of drugs. Previously, intermediate levels of resistance in Plasmodium falciparum were generated in vitro for artelinic acid (AL) and artemisinin (QHS). Here we expanded on earlier selection efforts to produce levels of clinically relevant concentrations, and the resulting lines w...
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تاریخ انتشار 2011